Introduction

Survival functions (client side) for DataSHIELD. DataSHIELD is a platform for federated analysis of private data. This package has client side functions for survival models and Cox models.

This is a standalone bolt on package for survival analysis in DataSHIELD.

• The server side package is called dsSurvival:

  • https://github.com/neelsoumya/dsSurvival

Installation

install.packages('devtools')

library(devtools)

devtools::install_github('neelsoumya/dsBaseClient')

devtools::install_github('neelsoumya/dsSurvivalClient')

• Install R Studio and the development environment as described below:

  • https://data2knowledge.atlassian.net/wiki/spaces/DSDEV/pages/12943461/Getting+started

• Then install the virtual machines as described below:

  • https://data2knowledge.atlassian.net/wiki/spaces/DSDEV/pages/931069953/Installation+Training+Hub-+DataSHIELD+v6

Usage

A tutorial in bookdown format is available here:

https://neelsoumya.github.io/dsSurvival_bookdown/

The meta-analyzed hazard ratios from a survival model are shown below.

Acknowledgements

We acknowledge the help and support of the DataSHIELD technical team. We are especially grateful to Paul Burton, Demetris Avraam, Stuart Wheater, Patricia Ryser-Welch and Wolfgang Vichtbauer for fruitful discussions and feedback.

Support or Contact

• Soumya Banerjee, Demetris Avraam, Paul Burton, Xavier Escriba Montagut, Juan Gonzalez and Tom R P Bishop

• sb2333@cam.ac.uk